Sulfadoxine-d4

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Chemical Structure| 1330266-05-1 同义名 : Sulphadoxine-d4
CAS号 : 1330266-05-1
货号 : A1268925
分子式 : C12H14N4O4S
纯度 : 98% 98%atom%D
分子量 : 314.354
MDL号 : MFCD34578246
存储条件:

Pure form Keep in dark place,Inert atmosphere,Room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 In drug development, the use of stable heavy isotopes such as hydrogen, carbon, and others in drug molecules primarily serves as a means for precise quantification during development phases. The process of deuteration, involving the substitution of hydrogen with its isotope deuterium, is noted for its potential to modify the pharmacokinetic and metabolic profiles of pharmaceuticals[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.18mL

0.64mL

0.32mL

15.91mL

3.18mL

1.59mL

31.81mL

6.36mL

3.18mL

参考文献

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.