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Pamidronate disodium salt hydrate

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Chemical Structure| 57248-88-1 同义名 : 帕米膦酸二钠 ;CGP 23339A;Pamidronate Disodium;Pamidronic Acid;APD;Pamidronate (sodium salt)
CAS号 : 57248-88-1
货号 : A126151
分子式 : C3H9NNa2O7P2
纯度 : 98% (contains H2O)
分子量 : 279.033
MDL号 : MFCD11045314
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Pamidronate disodium, a bisphosphonate drug, is used to strengthen bones.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.58mL

0.72mL

0.36mL

17.92mL

3.58mL

1.79mL

35.84mL

7.17mL

3.58mL
参考文献

[1]Viereck V, Emons G, et al. Bisphosphonates pamidronate and zoledronic acid stimulate osteoprotegerin production by primary human osteoblasts. Biochem Biophys Res Commun. 2002 Mar 1;291(3):680-6.

[2]Fitton A, McTavish D. Pamidronate. A review of its pharmacological properties and therapeutic efficacy in resorptive bone disease. Drugs. 1991 Feb;41(2):289-318. Review. Erratum in: Drugs 1992 Feb;43(2):145.