产品说明书
Dynarrestin
 |
同义名 : | - |
| CAS号 : | 2222768-84-3 | |
| 货号 : | A1251850 | |
| 分子式 : | C22H23F2N3O2S | |
| 纯度 : | 99%+ | |
| 分子量 : | 431.499 | |
| MDL号 : | MFCD32174341 | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 85 mg/mL(196.99 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Dynarrestin is an aminothiazole inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin rapidly and reversibly inhibits microtubule gliding driven by dyneins 1 in vitro, as well as a range of intracellular processes dependent on dyneins 1 and 2, without affecting ATP hydrolysis or interfering with ciliogenesis. Dynarrestin inhibits Hh-dependent proliferation of neuronal precursors and tumour cells[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.32mL 0.46mL 0.23mL |
11.59mL 2.32mL 1.16mL |
23.18mL 4.64mL 2.32mL |
| 参考文献 |
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