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25-Hydroxycholesterol

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Chemical Structure| 2140-46-7 同义名 : 25-OHC
CAS号 : 2140-46-7
货号 : A1251571
分子式 : C27H46O2
纯度 : 99%+
分子量 : 402.65
MDL号 : MFCD00057815
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 4 mg/mL(9.93 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

无水乙醇: 12 mg/mL(29.8 mM),配合低频超声助溶,注意:无水乙醇开封后,易挥发,也会吸收空气中的水分,导致溶解能力下降,请避免使用开封较久的乙醇

动物实验配方:
生物活性
描述 The synthesis of 25-Hydroxycholesterol is catalysed by cholesterol 25-hydroxylase, which uses cholesterol and molecular oxygen as substrates and NADPH as a cofactor. 25-Hydroxycholesterol is a potent biologically active lipid in the innate and adaptive immune system[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.48mL

0.50mL

0.25mL

12.42mL

2.48mL

1.24mL

24.84mL

4.97mL

2.48mL

参考文献

[1]McDonald JG, et al. Editorial: 25-Hydroxycholesterol: a new life in immunology. J Leukoc Biol. 2010 Dec;88(6):1071-2.