产品说明书

Tenuifolin

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Chemical Structure| 20183-47-5 同义名 : Presenegenin 3-O-glucoside
CAS号 : 20183-47-5
货号 : A124996
分子式 : C36H56O12
纯度 : 98%
分子量 : 680.823
MDL号 : MFCD20527302
存储条件：

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(154.23 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Tenuifolin, a natural product isolated and purified from the root of Polygala tenuifolia Willd., has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.47mL

0.29mL

0.15mL

7.34mL

1.47mL

0.73mL

14.69mL

2.94mL

1.47mL
参考文献

[1]Liu YM, Li ZY, et al. Tenuifolin, a secondary saponin from hydrolysates of polygalasaponins, counteracts the neurotoxicity induced by Aβ25-35 peptides in vitro and in vivo. Pharmacol Biochem Behav. 2015 Jan;128:14-22.

[2]Lv J, Jia H, et al. Tenuifolin, an extract derived from tenuigenin, inhibits amyloid-beta secretion in vitro. Acta Physiol (Oxf). 2009 Aug;196(4):419-25.