产品说明书

	同义名 :	LPS
	CAS号 :	93572-42-0
	货号 :	A1228298
	分子式 :	-
	纯度 :	>=500000 EU/mg
	分子量 :	0
	MDL号 :	MFCD00164401
	存储条件：	粉末 Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	Lipopolysaccharides，简称为 LPS，由连接单个或多个脂肪酸的碳水化合物单元组合而成，是革兰氏阴性菌（G-）细胞壁中的一种特有成分，位于细胞壁的最外层并暴露于非荚膜细菌的细胞表面，有利于维持细胞外膜的完整性，保护细菌免受胆汁盐和脂类抗生素的损害。 LPS可以引起免疫刺激的级联反应和机体的毒性病理生理活动，诱导生长促进因子如白介素的合成与分泌，诱导炎症疾病动物模型。Lipopolysaccharides from E. coli O55:B5 是从 E. coli O55:B5 中提取的 LPS。Lipopolysaccharides from E. coli O55:B5 激活免疫细胞的 TLR-4，可诱导神经炎症，心脏炎症，肝肾损伤等疾病模型[4-7]。

参考文献

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