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E3 ligase Ligand 10

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Chemical Structure| 1073560-68-5 同义名 : -
CAS号 : 1073560-68-5
货号 : A1220567
分子式 : C47H52N4O7
纯度 : 97%
分子量 : 784.938
MDL号 : MFCD32197258
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 E3 Ligase Ligand 10 serves as a ligand for E3 ubiquitin ligase. It can be attached to a protein's ligand via a linker to create PROTACs, which act as inducers for the ubiquitination-mediated breakdown of proteins that promote cancer[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.27mL

0.25mL

0.13mL

6.37mL

1.27mL

0.64mL

12.74mL

2.55mL

1.27mL
参考文献

[1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.