生物活性 | |||
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描述 | APX-115 is a potent, orally active pan-Nox inhibitor with Ki values of 1.08 μM, 0.57 μM and 0.63 μM for Nox1, Nox2 and Nox4, respectively[1].At a concentration of 5 μM for 60 min, APX-115 almost completely inhibited the expression of pro-inflammatory and necrotic molecules in high glucose-induced mouse podocyte cell lines[2]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.58mL 0.72mL 0.36mL |
17.90mL 3.58mL 1.79mL |
35.80mL 7.16mL 3.58mL |
参考文献 |
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