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Steviol

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Chemical Structure| 471-80-7 同义名 : Hydroxy Dehydrostevic Acid;NSC 226902;13-hydroxy Kaurenoic Acid;13-O-Glucosylsteviol
CAS号 : 471-80-7
货号 : A121554
分子式 : C20H30O3
纯度 : 99%+
分子量 : 318.45
MDL号 : MFCD00210558
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(329.72 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Steviol is the aglycon derivative of steviol glycosides, which are natural sweeteners isolated from S. rebaudiana. Steviol inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.14mL

0.63mL

0.31mL

15.70mL

3.14mL

1.57mL

31.40mL

6.28mL

3.14mL
参考文献

[1]Jaworska K, Krynitsky AJ, Rader JI. Simultaneous analysis of steviol and steviol glycosides by liquid chromatography with ultraviolet detection on a mixed-mode column: application to Stevia plant material and Stevia-containing dietary supplements. J AOAC Int. 2012 Nov-Dec;95(6):1588-96.

[2]Srimaroeng C, Jutabha P, et al. Interactions of stevioside and steviol with renal organic anion transporters in S2 cells and mouse renal cortical slices. Pharm Res. 2005 Jun;22(6):858-66.