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TTK21

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Chemical Structure| 709676-56-2 同义名 : -
CAS号 : 709676-56-2
货号 : A1210995
分子式 : C17H15ClF3NO2
纯度 : 97%
分子量 : 357.755
MDL号 : MFCD34565070
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(293.5 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 TTK21 is an activator of the histone acetyltransferases CBP/p300. TTK21 crosses the blood-brain barrier, is non-toxic, and reaches different parts of the brain when bound to glucose-based carbon nanospheres (CSPs). TTK21 has shown beneficial effects on brain functions such as neurogenesis and long-term memory in adults[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.80mL

0.56mL

0.28mL

13.98mL

2.80mL

1.40mL

27.95mL

5.59mL

2.80mL
参考文献

[1]Chatterjee S, et al. A novel activator of CBP/p300 acetyltransferases promotes neurogenesis and extends memory duration in adult mice. J Neurosci. 2013;33(26):10698-10712.