CDK1-IN-2

产品说明书

Print
Chemical Structure| 220749-41-7 同义名 : -
CAS号 : 220749-41-7
货号 : A1210613
分子式 : C17H11ClN2O
纯度 : 98%+
分子量 : 294.735
MDL号 : MFCD24369037
存储条件：

Pure form Inert atmosphere,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(848.22 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 CDK1-IN-2 is a CDK1 inhibitor with an IC50 value of 5.8 μM. At a concentration of less than 19.8 μM for 24 hours, CDK1-IN-2 causes HCT-116 cells to arrest in the G2/M phase[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.39mL

0.68mL

0.34mL

16.96mL

3.39mL

1.70mL

33.93mL

6.79mL

3.39mL
参考文献

[1]Jorda R, et al. How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases? J Med Chem. 2018 Oct 25;61(20):9105-9120.