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PHGDH-inactive

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Chemical Structure| 1914971-16-6 同义名 : 3-Phosphoglycerate Dehydrogenase-inactive
CAS号 : 1914971-16-6
货号 : A1209763
分子式 : C17H21N5S
纯度 : 97%
分子量 : 327.447
MDL号 : -
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 85 mg/mL(259.58 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 PHGDH-inactive has no activity against PHGDH and is a negative control for the compounds NCT-502 and NCT-503[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.05mL

0.61mL

0.31mL

15.27mL

3.05mL

1.53mL

30.54mL

6.11mL

3.05mL

参考文献

[1]Pacold ME, et al. A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate [published correction appears in Nat Chem Biol. 2016 Jul 19;12 (8):656]. Nat Chem Biol. 2016;12(6):452-458.