产品说明书

GSK3β inhibitor II

Print
Chemical Structure| 478482-75-6 同义名 : ​Glycogen Synthase Kinase 3β​​ Inhibitor II;Tip-oxadiazole;KIN 001-042;GSK-3 inhibitor II;Glycogen synthase kinase 3β inhibitor II
CAS号 : 478482-75-6
货号 : A1209676
分子式 : C14H10IN3OS
纯度 : 97%
分子量 : 395.218
MDL号 : -
存储条件:

粉末 Keep in dark place,Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(126.51 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 GSK3β Inhibitor II acts as a GSK3β inhibitor and is suitable for Alzheimer’s disease (AD) research[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.53mL

0.51mL

0.25mL

12.65mL

2.53mL

1.27mL

25.30mL

5.06mL

2.53mL

参考文献

[1]Elangovan ND, et al. Screening of potential drug for Alzheimer's disease: a computational study with GSK-3 β inhibition through virtual screening, docking, and molecular dynamics simulation. J Biomol Struct Dyn. 2021 Nov;39(18):7065-7079.