生物活性 | |||
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描述 | Tert-Butyl 11-aminoundecanoate serves as a PROTAC linker with a PEG-based structure. It is utilized in crafting a range of PROTACs, which are compounds comprising two distinct ligands linked together; one binds to an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs leverage the cellular ubiquitin-proteasome system for the selective elimination of target proteins[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.88mL 0.78mL 0.39mL |
19.42mL 3.88mL 1.94mL |
38.85mL 7.77mL 3.88mL |
参考文献 |
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