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n-Octyl β-D-glucopyranoside

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Chemical Structure| 29836-26-8 同义名 : n-Octylglucoside;BTB 11967
CAS号 : 29836-26-8
货号 : A118901
分子式 : C14H28O6
纯度 : 96%
分子量 : 292.368
MDL号 : MFCD00063288
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(359.14 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 n-Octyl β-D-glucopyranoside is a non-ionic descaling agent that can be widely used in biotechnology research, biochemical applications, solubilisation and crystallisation of membrane proteins. n-Octyl β-D-glucopyranoside completely inhibits cavitation-induced cell lysis in vitro[1][2][3].HL-60 cell suspensions were exposed to unfocused sonication at 1.057 MHz for 5-15 s with different alkyl glucopyranosides, and the addition of 2 mM n-Octyl β-D-glucopyranoside to the culture medium resulted in 100% cell survival after 5s of exposure, while cell lysis in the control group ranged from 35% to 100% in the control group[3].At 0.5 MPa exposure, n-Octyl β-D-glucopyranoside induced cavitation and lysis at 1 mM, but cavitation was reduced at 5 mM[3].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.42mL

0.68mL

0.34mL

17.10mL

3.42mL

1.71mL

34.20mL

6.84mL

3.42mL
参考文献

[1]Konidala P, et al. Molecular dynamics characterization of n-octyl-beta-D-glucopyranoside micelle structure in aqueous solution. J Mol Graph Model. 2006 Sep;25(1):77-86.

[2]Gould RJ, et al. Effects of octyl beta-glucoside on insulin binding to solubilized membrane receptors. Biochemistry. 1981 Nov 24;20(24):6776-81.

[3]Douglas L Miller, et al. The influence of octyl β-D-glucopyranoside on cell lysis induced by ultrasonic cavitation. J Acoust Soc Am. 2011 Nov;130(5):3482-8.