产品说明书

Coixol

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Chemical Structure| 532-91-2 同义名 : 6-Methoxy-2-benzoxazolinone;6-MBOA;MBOA;6-methoxybenzoxazolone
CAS号 : 532-91-2
货号 : A118406
分子式 : C8H7NO3
纯度 : 98%
分子量 : 165.146
MDL号 : MFCD00051726
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(635.8 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Coixol is a natural product isolated and purifed from the seeds of Coix lacryma-jobi L. var. meyuan (Romen.) Stapf. Coixol acts as a central muscle relaxant with an anti-convulsant effect, interacts with the pituitary to stimulate reproduction in voles. It also interacts with FSH to stimulate follicular development and increase ovulation. Coixol can regulate gene expression, production and secretion of mucin, by directly acting on airway epithelial cells.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.06mL

1.21mL

0.61mL

30.28mL

6.06mL

3.03mL

60.55mL

12.11mL

6.06mL
参考文献

[1]Willard ST, Dickerson T, et al. Administration of 6-methoxybenzoxazolinone (MBOA) does not augment ovulatory responses in St. Croix White ewes superovulated with PMSG. Anim Reprod Sci. 2006 Jul;93(3-4):280-91.

[2]Sweat FW, Berger PJ. Uterotropic 6-methoxybenzoxazolinone is an adrenergic agonist and a melatonin analog. Mol Cell Endocrinol. 1988 May;57(1-2):131-8.