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Betulonic acid

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Chemical Structure| 4481-62-3 同义名 : 白桦脂酮酸 ;(+)-Betulonic acid;Betunolic acid;Lup-20(29)-en-28-oic acid, 3-oxo-;NSC 152534;MJ347-RS;Liquidambaric acid
CAS号 : 4481-62-3
货号 : A117754
分子式 : C30H46O3
纯度 : 99+%
分子量 : 454.685
MDL号 : MFCD08459607
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 4 mg/mL(8.8 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Betulonic acid, a natural product isolated and purified from the branch of Eucalyptus globulus Labill., belongs to the pentacyclic triterpenic derivative class, has antitumor activities.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.20mL

0.44mL

0.22mL

11.00mL

2.20mL

1.10mL

21.99mL

4.40mL

2.20mL
参考文献

[1]Yang SJ, Liu MC, et al. Synthesis and biological evaluation of betulonic acid derivatives as antitumor agents. Eur J Med Chem. 2015;96:58-65.

[2]Dinh Ngoc T, Moons N, et al. Synthesis of triterpenoid triazine derivatives from allobetulone and betulonic acid with biological activities. Bioorg Med Chem. 2014 Jul 1;22(13):3292-300.