生物活性 | |||
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描述 | SW-100 is a selective HDAC6 inhibitor with an IC50 of 2.3 nM and is at least 1000 times more selective for HDAC6 than all other HDAC isozymes. SW-100 has significant blood-brain barrier permeability[1].SW-100 significantly increases acetylated α-tubulin levels in a dose-dependent manner over a concentration range of less than 10 µM for 48 hours[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.16mL 0.63mL 0.32mL |
15.78mL 3.16mL 1.58mL |
31.57mL 6.31mL 3.16mL |
参考文献 |
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