产品说明书
MARK4 inhibitor 1
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同义名 : | - |
| CAS号 : | 2271081-58-2 | |
| 货号 : | A1177000 | |
| 分子式 : | C20H18N6O3 | |
| 纯度 : | 98% | |
| 分子量 : | 390.395 | |
| MDL号 : | MFCD32693877 | |
| 存储条件： |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 4 mg/mL(10.25 mM)，配合低频超声，并调节pH至2，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | MARK4 inhibitor 1 is a potent and selective MARK4 inhibitor with an IC50 value of 1.54 μM. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis[1].In the concentration range of less than 200 µM for 24-48 hours, MARK4 inhibitor 1 inhibited cell proliferation and cell migration in a concentration-dependent manner, including MCF-7, MDA-MB-435s and HepG2 cells, with IC50 values of 6.22 μM, 9.94 μM and 8.14 μM, respectively[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.56mL 0.51mL 0.26mL |
12.81mL 2.56mL 1.28mL |
25.62mL 5.12mL 2.56mL |
| 参考文献 |
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