产品说明书

Orforglipron

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Chemical Structure| 2212020-52-3 同义名 : LY3502970;GLP-1 receptor agonist 1
CAS号 : 2212020-52-3
货号 : A1176829
分子式 : C48H48F2N10O5
纯度 : 99%+
分子量 : 882.956
MDL号 : MFCD31807602
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(118.92 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Orforglipron, also known as LY3502970, is a GLP-1 receptor agonist derived from patent WO2018056453A1. Orforglipron has multiple effects such as dependent delayed gastric emptying and feeding inhibition[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.13mL

0.23mL

0.11mL

5.66mL

1.13mL

0.57mL

11.33mL

2.27mL

1.13mL
参考文献

[1]Pyrazolopyridine derivative having glp-1 receptor agonist effect. WO2013046136A1.