产品说明书

Elinogrel

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Chemical Structure| 936500-94-6 同义名 : PRT060128;PRT128
CAS号 : 936500-94-6
货号 : A1176677
分子式 : C20H15ClFN5O5S2
纯度 : 98%
分子量 : 523.945
MDL号 : MFCD16619373
存储条件：

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 60 mg/mL(114.52 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Elinogrel, known as PRT060128, is a potent, direct, competitive and reversible platelet P2Y12 antagonist with an IC50 value of 20 nM. It can be administered orally and intravenously and has potent antiplatelet effects[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.91mL

0.38mL

0.19mL

9.54mL

1.91mL

0.95mL

19.09mL

3.82mL

1.91mL
参考文献

[1]Angiolillo DJ, et al. Pharmacokinetic and pharmacodynamic effects of elinogrel: results of the platelet function substudyfrom the intravenous and oral administration of elinogrel to evaluate tolerability and efficacy in nonurgent percutaneous coronary int