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PP7

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Chemical Structure| 433238-84-7 同义名 : -
CAS号 : 433238-84-7
货号 : A1176407
分子式 : C18H14Cl2N2O3
纯度 : 99%+
分子量 : 377.221
MDL号 : -
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 PP7 effectively inhibits the interaction between PB1 and PB2 with an IC50 of 8.6 μM and also hinders viral polymerase activity with an IC50 of 9.5 μM. It exhibits antiviral properties against various strains of influenza A virus, including A(H1N1)pdm09 with an EC50 of 1.4 μM, as well as A(H7N9) and A(H9N2) subtypes[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.65mL

0.53mL

0.27mL

13.25mL

2.65mL

1.33mL

26.51mL

5.30mL

2.65mL

参考文献

[1]Yuan S, et al. Identification of a novel small-molecule compound targeting the influenza A virus polymerase PB1-PB2 interface. Antiviral Res. 2017 Jan;137:58-66.