产品说明书
Primaquine
 |
同义名 : | - |
| CAS号 : | 90-34-6 | |
| 货号 : | A116308 | |
| 分子式 : | C15H21N3O | |
| 纯度 : | 95% HPLC | |
| 分子量 : | 259.347 | |
| MDL号 : | MFCD00598906 | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 250 mg/mL(963.96 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Primaquine serves as an effective antimalarial drug and a strong gametocytocide for falciparum malaria. It also prevents relapses in vivax and ovale malaria[1][2]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT01659281 | Plasmodium Falciparum Malaria | Not Applicable | Completed | - | Thailand ... 展开 >> Vector Borne Diseases Control Units (VBDC, malaria clinics) Borai, Khaosaming and Muang districts, Trat, Thailand, 23000 收起 << |
| NCT03726593 | Plasmodium Falciparum Malaria ... 展开 >>(Drug Resistant) 收起 << | Phase 4 | Recruiting | June 30, 2021 | Cambodia ... 展开 >> Kratie Referral Hospital Not yet recruiting Kratie, Cambodia Contact: Somaly Kieng, M.D +855 72 971 755 Contact: Chanthap Lon, M.D 855 23 881 845 chanthapl@afrims.org Sub-Investigator: Darapiseth Sea, MD Sub-Investigator: Dysoley Lek, MD Anlong Veng Referral Hospital Recruiting Ânlóng Vêng, Cambodia Contact: Phan Kong, M.A 016 51 09 09 Principal Investigator: Chanthap Lon, MD Sub-Investigator: Darapiseth Sea, MD Sub-Investigator: Dysoley Lek, MD 收起 << |
| NCT02528279 | Malaria | Not Applicable | Completed | - | Gabon ... 展开 >> Centre de Recherches Médicales de Lambaréné, Hôpital Albert Schweitzer Lambaréné, Moyen-Ogooué, Gabon, 118 Centre de Recherches Médicales de Ngounié Fougamou, Ngounié, Gabon, 113 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.86mL 0.77mL 0.39mL |
19.28mL 3.86mL 1.93mL |
38.56mL 7.71mL 3.86mL |
| 参考文献 |
|---|
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[1]Ashley EA, et al. Primaquine: the risks and the benefits. Malar J. 2014 Nov 3;13:418. |