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Aminooxy-PEG1-propargyl

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Chemical Structure| 1895922-69-6 同义名 : -
CAS号 : 1895922-69-6
货号 : A1159765
分子式 : C5H9NO2
纯度 : 98%
分子量 : 115.13
MDL号 : MFCD29764324
存储条件：

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Aminooxy-PEG1-propargyl is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs[1]. Aminooxy-PEG1-propargyl is a click chemistry reagent featuring an Alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

8.69mL

1.74mL

0.87mL

43.43mL

8.69mL

4.34mL

86.86mL

17.37mL

8.69mL
参考文献

[1]Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.