产品说明书

MAO-B-IN-8

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Chemical Structure| 1638956-60-1 同义名 : -
CAS号 : 1638956-60-1
货号 : A1155518
分子式 : C18H16O6
纯度 : 97%
分子量 : 328.316
MDL号 : MFCD04145698
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 120 mg/mL(365.5 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 MAO-B-IN-8 is a potent, reversible MAO-B inhibitor that also inhibits microglial production of neuroinflammatory mediators. It is applicable for research into neurodegenerative diseases[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.05mL

0.61mL

0.30mL

15.23mL

3.05mL

1.52mL

30.46mL

6.09mL

3.05mL

参考文献

[1]Elangovan ND, et al. Screening of potential drug for Alzheimer's disease: a computational study with GSK-3 β inhibition through virtual screening, docking, and molecular dynamics simulation. J Biomol Struct Dyn. 2021 Nov;39(18):7065-7079.