产品说明书

WYC-209

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Chemical Structure| 2131803-90-0 同义名 : -
CAS号 : 2131803-90-0
货号 : A1155098
分子式 : C20H20N2O3S
纯度 : 99%+
分子量 : 368.449
MDL号 : N/A
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 85 mg/mL(230.7 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 WYC-209, a synthetic retinoid, acts as an agonist for the retinoic acid receptor (RAR). It primarily triggers apoptosis through the caspase 3 pathway (with an IC50 of 0.19 μM in malignant murine melanoma TRCs), and exhibits prolonged effects with minimal toxicity [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.71mL

0.54mL

0.27mL

13.57mL

2.71mL

1.36mL

27.14mL

5.43mL

2.71mL
参考文献

[1]Chen J, et al. Inhibition of cancer stem cell like cells by a synthetic retinoid. Nat Commun. 2018 Apr 11;9(1):1406.