生物活性 | |||
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描述 | Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthetic E3 ligase ligand-linker conjugate featuring a cereblon ligand based on Thalidomide and a 2-unit PEG linker, used in PROTAC technology[1]. Thalidomide-O-PEG2-propargyl serves as a click chemistry reagent, featuring an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that possess Azide groups. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.50mL 0.50mL 0.25mL |
12.49mL 2.50mL 1.25mL |
24.98mL 5.00mL 2.50mL |
参考文献 |
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