生物活性 | |||
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靶点 |
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描述 | Quercetin is a natural flavonoid that can activate SIRT1, inhibit PI3K, inhibit PI3K γ, PI3K δ, PI3K β, with IC50[3]. In vitro,the IC50[4]. In vivo, combination of quercetin and 2-ME can serve as a novel clinical treatment regimen owning the potential of enhancing antitumor effect on prostate cancer and lessening the dose and side effects of either quercetin or 2-ME alone[5]. |
临床研究 | |||||
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NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT01881919 | Hyperuricemia ... 展开 >> Gout Kidney Calculi Diabetes Cardiovascular Disease 收起 << | Early Phase 1 | Completed | - | United Kingdom ... 展开 >> School of Food Science and Nutrition Leeds, West Yorkshire, United Kingdom, LS2 9JT 收起 << |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.96mL 0.59mL 0.30mL |
14.78mL 2.96mL 1.48mL |
29.56mL 5.91mL 2.96mL |
参考文献 |
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