Crocetin disodium
产品说明书
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同义名 : | 藏红花 ;trans-Crocetin disodium |
| CAS号 : | 591230-99-8 | |
| 货号 : | A1144572 | |
| 分子式 : | C20H22Na2O4 | |
| 纯度 : | 97% | |
| 分子量 : | 372.366 | |
| MDL号 : | MFCD22572782 | |
| 存储条件： |
Pure form Inert atmosphere,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
H2O: 15 mg/mL(40.28 mM)，配合低频超声助溶 |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Crocetin (Transcrocetin, trans-Crocetin) disodium, a metabolite derived from saffron's crocin apocarotenoids, is noted for its strong affinity to NMDA receptors, suggesting a potential mechanism behind saffron's CNS activity. in vitro studies utilizing Caco-2 cells have indicated that cellular viability remains unchanged after a 24-hour incubation with hydroalcoholic saffron extract (SE, 0.5-1 mg/mL) and crocin-1 (250-1000 µM). However, while Crocetin disodium at a concentration of 10 µM does not impact cell viability, higher concentrations (40-160 µM) significantly reduce it[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.69mL 0.54mL 0.27mL |
13.43mL 2.69mL 1.34mL |
26.86mL 5.37mL 2.69mL |
| 参考文献 |
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