H-D-Ala-OH

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Chemical Structure| 338-69-2 同义名 : (R)-Alanine;Ba 2776;NSC 158286;Ala;D-α-Alanine
CAS号 : 338-69-2
货号 : A109670
分子式 : C3H7NO2
纯度 : 98%+
分子量 : 89.093
MDL号 : -
存储条件：

Pure form Keep in dark place,Inert atmosphere,Room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 120 mg/mL(1346.9 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 D-Alanine acts as a modest agonist for the inhibitory glycine receptor (GlyR) and PMBA, with an EC50 of 9 mM for GlyR[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

11.22mL

2.24mL

1.12mL

56.12mL

11.22mL

5.61mL

112.24mL

22.45mL

11.22mL
参考文献

[1]Schmieden V, et al. Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol Pharmacol. 1995 Nov;48(5):919-27.

[2]Saitoh T, et al. A novel antagonist, phenylbenzene omega-phosphono-alpha-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br J Pharmacol. 1994 Sep;113(1):165-70.

[3]Mao Horio, et al. Effects of D-Amino Acid Oxidase Inhibitor on the Extracellular D-Alanine Levels and the Efficacy of D-Alanine on Dizocilpine-Induced Prepulse Inhibition Deficits in Mice. The Open Clinical Chemistry Journal, 2009, 2: 16-21