产品说明书

Riboflavin phosphate sodium

Print
Chemical Structure| 130-40-5 同义名 : 维生素B2 ;FMN-Na;Riboflavin 5'-phosphate sodium;Riboflavin 5-phosphate sodium;Hyryl;Riboflavin Sodium Phosphate;FMN;riboflavin-5'-phosphate;Flavin mononucleotide;Vitamin B2 Phosphate Sodium Salt
CAS号 : 130-40-5
货号 : A107667
分子式 : C17H20N4NaO9P
纯度 : 71% (HPLC)
分子量 : 478.326
MDL号 : MFCD00065362
存储条件:

粉末 Inert atmosphere,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

H2O: 20 mg/mL(41.81 mM),配合低频超声,并水浴加热至45℃助溶

动物实验配方:
生物活性
描述 Riboflavin phosphate sodium (FMN-Na), a derivative of riboflavin (vitamin B2), is vital for animal nutrition. It is commonly utilized in research focusing on eye conditions such as progressive keratoconus, corneal ectasia, and irregular astigmatism[1].[2]. Riboflavin phosphate sodium has been identified as a highly effective NAD+-recycling agent[3].
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02095730 Unstable Corneas Phase 3 Unknown - United States, California ... 展开 >> LaserVue Eye Not yet recruiting Santa Rosa, California, United States, 95403 Contact: Jay Bansal, MD    707-522-6200    bansal@laservue.com    Principal Investigator: Jay Bansal, MD          United States, Colorado Icon Lasik Not yet recruiting Denver, Colorado, United States, 80210 Contact: Richard Anderson, OD    720-524-1001    ra@icondenver.com    Principal Investigator: Douglas Campbell, DO          United States, Florida Gulani Vision Institute Not yet recruiting Jacksonville, Florida, United States, 32216 Contact: Arun Gulani, MD    904-296-7393    gulanivision@gulani.com    Principal Investigator: Arun Gulani, MD          United States, Georgia Eye Consultants of Atlanta Not yet recruiting Atlanta, Georgia, United States, 30339 Contact: Teresa Long    404-351-2220    teresa_long@eyeconsultants.net    Principal Investigator: W. Barry Lee, MD          United States, Illinois Midwest Center for Sight Not yet recruiting Des Plaines, Illinois, United States, 60016 Contact: James Katz, MD    847-824-3127    jamesakatz@aol.com    Principal Investigator: James Katz, MD          Bond Eye Associates Not yet recruiting Pekin, Illinois, United States, 61554 Contact: William Bond, MD    309-353-6660    pekineye@yahoo.com    Principal Investigator: William Bond, MD          United States, Kansas Discover Vision Center Not yet recruiting Leawood, Kansas, United States, 66211 Contact: Misty Robe, Associate's    816-478-1230    mrobe@discovervision.com    Principal Investigator: John Doane, MD          United States, Mississippi Southern Eye Center Not yet recruiting Hattiesburg, Mississippi, United States, 39402 Contact: Cameron Griffith, MD    318-464-0306    csgriff1@earthlink.net    Principal Investigator: Cameron Griffith, MD          United States, Missouri Mercy Clinic Eye Specialists Not yet recruiting Springfield, Missouri, United States, 65807 Contact: Stephanie Sekscinski    417-820-9393    stephanie.sekscinski@mercy.net    Principal Investigator: Shachar Tauber, MD          United States, Nevada LASIK of Nevada Not yet recruiting Las Vegas, Nevada, United States, 89123 Contact: Valerie Serett    702-636-2010    vserette@yahoo.com    Principal Investigator: Richard Rothman, MD          Sub-Investigator: Rajy Rouweyha, MD          United States, Pennsylvania James Lewis MD PC Not yet recruiting Elkins Park, Pennsylvania, United States, 19027 Contact: James Lewis, MD    215-886-9090    jslewis@jameslewis.com    Principal Investigator: James Lewis, MD          Memorial Eye Institute Not yet recruiting Harrisburg, Pennsylvania, United States, 17112 Contact: Sherrie Reed    717-657-2020    crosslinkstudy@memorialeye.com    Principal Investigator: Bennett Chotiner, MD          Principal Investigator: Erik Chotiner, MD          United States, South Carolina Carolina Eye Care Not yet recruiting Mt. Pleasant, South Carolina, United States, 29464 Contact: Helga Sandoval, MD    843-881-3937    helga.sandoval@carolinaeyecare.com    Principal Investigator: Kerry Solomon, MD          Sub-Investigator: Charlene Grice, MD          United States, Tennessee Loden Vision Centers Not yet recruiting Goodlettsville, Tennessee, United States, 37072 Contact: Katie Lambeth    615-859-3937    klamberth@lodenvision.com    Principal Investigator: James Loden, MD          United States, Texas Parkhurst NuVision Not yet recruiting San Antonio, Texas, United States, 78229 Contact: Amy Ford    210-428-6788    nuvision.amy@gmail.com    Principal Investigator: Gregory D Parkhurst, MD          United States, Virginia Liberty Laser Eye Center Not yet recruiting Vienna, Virginia, United States, 22182 Contact: Travis A Johnson, Bachelor's    571-234-5678 ext 104    tjohnson@libertylasereye.com    Principal Investigator: Nancy A Tanchel, MD 收起 <<
NCT03469232 Intense-exuberant Stomach Fire... 展开 >> Syndrom Acute Pericoronitis Recurrent Aphthous Stomatitis Recurrent Herpes Simplex Labialis 收起 << Phase 1 Phase 2 Recruiting November 1, 2018 China, Beijing ... 展开 >> Third affiliated hospital of Beijing University of traditional Chinese medicine Recruiting Beijing, Beijing, China, 100029 Contact: Lu Qiang, Professor    8610-52075325       Principal Investigator: Lu Qiang, Professor          Dongfang Hospital Affiliated to Beijing University of traditional Chinese medicine Recruiting Beijing, Beijing, China, 100078 Contact: Hong Mu, Professor    010-67618333       Principal Investigator: Hong Mu, Professor          China, Sichuan Affiliated Hospital to Chengdu University of traditional Chinese medicine Recruiting Chengdu, Sichuan, China, 610075 Contact: Yuling Zuo, Professor    028-87769902       Principal Investigator: Yuling Zuo, Professor 收起 <<
NCT02117999 Progressive Keratoconus Not Applicable Completed - Italy ... 展开 >> Fondazione G.B. Bietti, IRCCS Rome, Italy, 00198 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.09mL

0.42mL

0.21mL

10.45mL

2.09mL

1.05mL

20.91mL

4.18mL

2.09mL

参考文献

[1]José Luis Revuelta, et al. Bioproduction of riboflavin: a bright yellow history. J Ind Microbiol Biotechnol. 2017 May;44(4-5):659-665.

[2]Carmine Ostacolo, et al. Enhancement of corneal permeation of riboflavin-5'-phosphate through vitamin E TPGS: a promising approach in corneal trans-epithelial cross linking treatment. Int J Pharm. 2013 Jan 20;440(2):148-53.

[3]J. Bryan Jones, et al. Nicotinamide coenzyme regeneration. Flavin mononucleotide (riboflavin phosphate) as an efficient, economical, and enzyme-compatible recycling agent. Can J Chem. 1976, 54(19): 2969-2973,