生物活性 | |||
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描述 | ICCB-19 hydrochloride is a TRADD (TNFRSF1A associated via death domain) inhibitor. It binds to the N-terminal domain of TRADD (TRADD-N), disrupting its interaction with both TRADD-C and TRAF2. ICCB-19 hydrochloride indirectly inhibits RIPK1 kinase activity, effectively inducing autophagy and the degradation of long-lived proteins[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.43mL 0.69mL 0.34mL |
17.13mL 3.43mL 1.71mL |
34.27mL 6.85mL 3.43mL |
参考文献 |
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