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Gartanin

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Chemical Structure| 33390-42-0 同义名 : -
CAS号 : 33390-42-0
货号 : A103931
分子式 : C23H24O6
纯度 : 98%
分子量 : 396.433
MDL号 : MFCD09264654
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(302.7 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Gartanin, a natural product isolated and purified from the stem bark of Garcinia mangostana, possesses antifungal, antioxidant, anti‑inflammatory and antineoplastic properties, can be a multiple targeting agent into its chemopreventive properties for human urinary bladder cancer, and induces protective autophagy mainly by JNK-Bcl-2 pathway.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.52mL

0.50mL

0.25mL

12.61mL

2.52mL

1.26mL

25.22mL

5.04mL

2.52mL
参考文献

[1]Kim MO, Lee HS, et al. Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosis. Oncol Rep. 2015 Jul;34(1):139-46.

[2]Liu Z, Antalek M, et al. The effect of gartanin, a naturally occurring xanthone in mangosteen juice, on the mTOR pathway, autophagy, apoptosis, and the growth of human urinary bladder cancer cell lines. Nutr Cancer. 2013;65 Suppl 1:68-77.