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Ganoderic acid B

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Chemical Structure| 81907-61-1 同义名 : -
CAS号 : 81907-61-1
货号 : A101516
分子式 : C30H44O7
纯度 : 98%
分子量 : 516.666
MDL号 : MFCD09752803
存储条件:

粉末 2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(96.77 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Ganoderic acid B, a natural product isolated and purified from the fruit body of Ganoderma lucidum, is a moderately active inhibitor against HIV-1 protease with a 50% inhibitory concentration of 0.17-0.23 mM.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.94mL

0.39mL

0.19mL

9.68mL

1.94mL

0.97mL

19.35mL

3.87mL

1.94mL

参考文献

[1]Guo J, Ni C, et al. Ganoderic acid B's influence towards the therapeutic window of trifluoperazine (TFP). Afr Health Sci. 2015 Mar;15(1):146-9.

[2]Guo X, Shen X, et al. Structural identification of the metabolites of ganoderic acid B from Ganoderma lucidum in rats based on liquid chromatography coupled with electrospray ionization hybrid ion trap and time-of-flight mass spectrometry. Biomed Chromatogr. 2013 Sep;27(9):1177-87.