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HTHQ

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Chemical Structure| 148081-72-5 同义名 : HX-1171;1-O-hexyl-2,3,5-trimethylhydroquinone;BTT-105
CAS号 : 148081-72-5
货号 : A100799
分子式 : C15H24O2
纯度 : 98%
分子量 : 236.35
MDL号 : MFCD00797612
存储条件:

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(444.26 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 HTHQ, which is a hydroquinone monoalkyl ether, is a potent anti-oxidative agent, even at low dose levels.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.23mL

0.85mL

0.42mL

21.16mL

4.23mL

2.12mL

42.31mL

8.46mL

4.23mL

参考文献

[1]Hino T, Kawanishi S, et al. HTHQ (1-O-hexyl-2,3,5-trimethylhydroquinone), an anti-lipid-peroxidative compound: its chemical and biochemical characterizations. Biochim Biophys Acta. 1998 Sep 16;1425(1):47-60.

[2]Hirose M, Hasegawa R, et al. Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[1,2-a:3',2'-d] imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dimethylimidazo[4,5-f] quinoxaline (MeIQx). Carcinogenesis. 1995 Dec;16(12):3049-55.