产品说明书
USL311
 |
同义名 : | - |
| CAS号 : | 1373268-67-7 | |
| 货号 : | A1001764 | |
| 分子式 : | C24H34N6O | |
| 纯度 : | 99%+ | |
| 分子量 : | 422.566 | |
| MDL号 : | N/A | |
| 存储条件： |
粉末 Inert atmosphere,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 18 mg/mL(42.6 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Chemokines and chemokine receptors regulate multiple processes such as morphogenesis, angiogenesis and immune responses. Among the chemokine receptors, CXCR4 stands out for its pleiotropic roles as well as for its involvement in several pathological conditions, including immune diseases, viral infections and cancer[1]. USL311, a selective CXCR4 antagonist, exhibits an anti-tumor activity. USL311 prevents the binding of stromal-cell derived factor-1 (SDF-1) to CXCR4[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.37mL 0.47mL 0.24mL |
11.83mL 2.37mL 1.18mL |
23.66mL 4.73mL 2.37mL |
| 参考文献 |
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